Not really....... imo
If you think they do, then your power wire, and speaker wires make a difference in sound quality too (a bigger gauge cable just wont be good enough)...
The only thing a RCA can really change is its noise shielding quality, and well if you run your RCAs proper you should have no engine noise or whine, even when using cheap cables with absolutist zero shielding.
No sense dropping bank on cables if your running amps that cost $300-600 each, and $200 component speakers, etc.
Thats nonsens it would help realy, it can be realy like, that it sounds this much better, that you can think you have upgraded aour amps and HU on a level category higher.