Big question, how much power are you going to run? That is going to greatly affect what subs you should pick and how flat of response you can achieve.
Here are some things to think about:
1. Ported boxes boost output around tuning. Once you get about an octave above tuning, the port has no effect. So at 70 Hz a 25 Hz tune is going to sound exactly the same as a 32 hz tuning.
2. The larger you make a ported box, the more boost in output you get, but only around tuning. If you want smoother frequency response, making the box smaller is one way to do that.
3. If you care about frequency response, don't run 8" subs unless you can't fit anything else. The problem with 8" subs is if they have moderately high power handling (which for 8"s is anything above 300 watts RMS, IMHO) they generally have really stiff suspensions and high motor force to cone area ratios, both of these things are bad for getting smooth frequency response. Compared to larger subs 8" subs will also have limited Xmax due to the fact that you can only fit so big of a spider on them. I'll say it again, there is no reason to run 8" subs if you can fit something larger.
4. If you are after smoother frequency response there are several ways to accomplish that goal.
- Run larger subs, larger subs GENERALLY have lower motor force to cone area ratios, makes it easier to get smoother frequency response. I'd take one 15" over two 12"s or three 10"s almost every single time.
- Make the ported box smaller. Smaller ported boxes boost the low end less, making it much less likely you will end up with peaky response.
- Run sealed. With a sealed box you don't get any low frequency boost. The low end roll off of a proper sealed box closely matches the cabin gain you get in most vehicles, giving you pretty flat frequency response.
- Do like strangeduck suggested and run a ported box and EQ it flat. This is the mostly complex option, but its also the most flexible. You can get whatever frequency response you want and you can change it around really easily. Just keep in mind its easy to turn down peaks with EQ, its almost impossible to fix dips in output though. DSP/EQ is pretty cheap these days, you can get a miniDSP for a little over $100. This is what I'm doing in my own vehicle.
If I were in your shoes I'd probably try to cram two 12"s subs in a ported box if at all possible (what's the max dimensions of your space?), if its not go for two 10"s. I'd be picky about what subs I used and I'd probably use EQ to dial in exactly how it wanted them to sound.